TY - JOUR AU - Mustamu, Hillary L. AU - Evacuasiany, Endang AU - Liana, Laella K. PY - 2016/02/28 Y2 - 2024/03/28 TI - The Ethanol Extract of Neem Leaf (Azadirachta Indica A. Juss) Effect towards Wound Healing in Male Swiss Webster Mice JF - Journal of Medicine and Health JA - J. Med. Health VL - 1 IS - 3 SE - Articles DO - 10.28932/jmh.v1i3.519 UR - https://journal.maranatha.edu/index.php/jmh/article/view/519 SP - AB - accelerates wound healing. We examined the effect of Ethanol Extract of Neem Leaf (EENL) in<br />accelerating wound healing and compared its potential with povidone iodine. This was an<br />analytic experimental study, using Complete Randomized Design (CRD) with a comparative<br />method. We used 30 male Swiss Webster mice that were divided into five groups (n=6). Each<br />group was given the Ethanol Extract of Neem Leaf (EENL) with a concentration of 25%, 12.5%<br />and 25%, aquades (negative control) and povidone iodine 10% (comparison). The average<br />wound healing time of EENL 25%, EENL 12.5% , EENL 6.25% , povidone iodine and aquades<br />were 11.2; 12.2;13.2;13.2;and 1.3 days respectively. The data was analized with one way<br />ANOVA and showed a highly significant difference of p=0.000. Tukey HSD test showed that<br />EENL 25% and 12.5% had better potential than povidone iodine 10% and EENL 6.25% had the<br />same potential with povidone iodine 10%. This study concludes that ethanol extract of neem leaf<br />has an effect in accelerating the duration of wound healing, with EENL 25% as the best<br />concentration in accelerating the duration of wound healing.<br />Keywords: neem leaf, Azadirachta indica A. Juss, wound healing, Swiss Webster mice ER -