TY - JOUR AU - Onggowidjaja, Philips AU - Shahib, M. Nurhalim PY - 2015/08/31 Y2 - 2024/03/28 TI - THE INFLUENCE OF COMMON CARP MEAT (Cyprinus carpio) DIET ON BRAIN INDEX AND THE EXPRESSION OF GENE NR2B OF SWISS WEBSTER MICE CEREBRUM JF - Journal of Medicine and Health JA - J. Med. Health VL - 1 IS - 2 SE - Articles DO - 10.28932/jmh.v1i2.505 UR - https://journal.maranatha.edu/index.php/jmh/article/view/505 SP - AB - <p><em>This research was to evaluate the influence of common carp meat diet on brain index and  gene NR2B expression</em><em> of  Swiss Webster mice cerebrum</em><em>.  The gene expression and performance of ion Ca<sup>2+ </sup>channel in neuron are influenced by Glycine and Glutamic Acid, which present in relatively high quantities in common carp meat.  Eighteen male mice were divided into 3 diet groups, the standard pellet, 120 mg and 480 mg common carp meat/day.  The brain index differences among groups were analyzed using ANOVA test (p≤0,05) and LSD.  The total RNA of 5 mg mouse cerebrum was isolated, followed by RT-PCR; the DNA quantities were predicted using Geldoc instrument, then were analyzed using ANOVA test (p≤0,05).  The 120 mg diet group brain index did not show difference (p=0,284) against the standard diet group, while the 480 mg diet group showed the increase compared to the standard (p=0,034) and 120 mg diet groups (p=0,004).  No DNA quantity differences of all groups (p=0,195).  It was concluded, the 480 mg common carp meat/ day diet increased the brain index of Swiss Webster mice, while the 120 mg and 480 mg common carp/day diets did not influence the gene NR2B expression</em><em> of Swiss Webster mice cerebrum.</em></p><p><em> </em><strong><em>Keywords</em></strong><em> : brain index, gene NR2B expression, common carp meat diet</em></p> ER -