@article{Prahastuti_Hidayat_Kurniadi_Christiany_2016, place={Bandung, Indonesia}, title={Potency of Black Soybean (Glycine max L. Merr) and Jati Belanda Leaves (Guazuma ulmifolia Lamk) for Dyslipidemia Treatment In Vivo}, volume={1}, url={https://journal.maranatha.edu/index.php/jmh/article/view/515}, DOI={10.28932/jmh.v1i3.515}, abstractNote={<p><em>S</em><em>oybean Detam 1 and</em><em> Jati Belanda leaves</em><em> </em><em>are potential alternative medicines for treating </em><em>dyslipidemia. The purpose of this study </em><em>is</em><em> to </em><em>explore </em><em> the potential of the combination of Ethanol</em><em>ic</em><em> Extract Soybean Detam 1 (EEKD) and Jati Belanda (EEJB) in lowering LDL cholesterol and triglycerides compared to sing</em><em>le</em><em> extract and Simvastatin. Using a real laboratory experimental method with CRD</em><em>,</em><em> </em><em>a</em><em> total of 36 male Wistar rats were divided into 6 groups</em><em> and administrated for</em><em> </em><em>treatment of</em><em> 28 days. The results showed </em><em>a </em><em>significant </em><em>decrease of LDL cholesterol as well as triglyceride in NC  as compared to P1, P2, P3 </em><em>(p <0.05) </em><em>and </em><em>no significant difference with PC (p</em><em>></em><em> 0.05)</em><em>. The highest suppression of LDL cholesterol between </em><em>P</em><em>1</em><em> </em><em>with P2 and </em><em>P3 </em><em>is </em><em>(p <0.05</em><em>) while the triglyceride is between P1 and </em><em>P2 (p <0.05</em><em>). This study concludes that the c</em><em>ombination</em><em> of </em><em>EEKD 10 mg, 20 mg EEJB</em><em>, EEKD 30 mg and EEJB 30 mg</em><em> </em><em>is significantly lowering LDL cholesterol and triglyceride. The c</em><em>ombination</em><em> of </em><em>EEKD 10 mg, 20 mg EEJB</em><em> is the highest compression of LDL cholesterol and triglyceride, and has an equivalent effect with </em><em>simvastatin in lowering LDL cholesterol and triglycerides in male Wistar rats induced </em><em>with high fat diet.</em></p><p><em> </em></p><p><strong><em>Keywords:</em></strong><strong><em> </em></strong><em>LDL</em><em> ch</em><em>olesterol, </em><em>triglycerides</em><em></em></p>}, number={3}, journal={Journal of Medicine and Health}, author={Prahastuti, Sijani and Hidayat, Meilinah and Kurniadi, Michael W. and Christiany, Selvina}, year={2016}, month={Feb.} }