@article{Onggowidjaja_Shahib_2015, place={Bandung, Indonesia}, title={THE INFLUENCE OF COMMON CARP MEAT (Cyprinus carpio) DIET ON BRAIN INDEX AND THE EXPRESSION OF GENE NR2B OF SWISS WEBSTER MICE CEREBRUM}, volume={1}, url={https://journal.maranatha.edu/index.php/jmh/article/view/505}, DOI={10.28932/jmh.v1i2.505}, abstractNote={<p><em>This research was to evaluate the influence of common carp meat diet on brain index and  gene NR2B expression</em><em> of  Swiss Webster mice cerebrum</em><em>.  The gene expression and performance of ion Ca<sup>2+ </sup>channel in neuron are influenced by Glycine and Glutamic Acid, which present in relatively high quantities in common carp meat.  Eighteen male mice were divided into 3 diet groups, the standard pellet, 120 mg and 480 mg common carp meat/day.  The brain index differences among groups were analyzed using ANOVA test (p≤0,05) and LSD.  The total RNA of 5 mg mouse cerebrum was isolated, followed by RT-PCR; the DNA quantities were predicted using Geldoc instrument, then were analyzed using ANOVA test (p≤0,05).  The 120 mg diet group brain index did not show difference (p=0,284) against the standard diet group, while the 480 mg diet group showed the increase compared to the standard (p=0,034) and 120 mg diet groups (p=0,004).  No DNA quantity differences of all groups (p=0,195).  It was concluded, the 480 mg common carp meat/ day diet increased the brain index of Swiss Webster mice, while the 120 mg and 480 mg common carp/day diets did not influence the gene NR2B expression</em><em> of Swiss Webster mice cerebrum.</em></p><p><em> </em><strong><em>Keywords</em></strong><em> : brain index, gene NR2B expression, common carp meat diet</em></p>}, number={2}, journal={Journal of Medicine and Health}, author={Onggowidjaja, Philips and Shahib, M. Nurhalim}, year={2015}, month={Aug.} }