@article{Puspitasari_Henrica_2020, place={Bandung, Indonesia}, title={A Case of Lupus Vulgaris Diagnosed without Skin Biopsy}, volume={2}, url={https://journal.maranatha.edu/index.php/jmh/article/view/1839}, DOI={10.28932/jmh.v2i5.1839}, abstractNote={<p><em>Lupus vulgaris is a variant of cutaneous tuberculosis in a previously sensitized individual that has a high degree of delayed-type hypersensitivity to tuberculin. Absolute criteria for the diagnosis of cutaneous tuberculosis is a positive M. tuberculosis culture on guinea pig or polymerase chain reaction (PCR) examination</em><em>. </em><em>We reported a case of lupus vulgaris in a 32 years old female. A diagnosis of lupus vulgaris was made by clinical manifestation, therapeutic trial, interferon-gamma release assay (IGRA) test, and other laboratory tests.</em> <em>The patient presented with an erythematous scaly plaque on the face and left hand. Diascopy test was positive, consistent with the “apple jelly” sign. Regression of lesion was observed after 1 month of therapy with ant</em><em>i-</em><em>tuberculosis drugs. Culture, PCR, and histopathological examination were not established due to patient’s refusal.</em> <em>The patient was allergic to pyrazinamide and ethambutol, therefore she was initially treated with a daily dose of 450 mg Rifampicin, 300 mg isoniazid (INH), and 500 mg levofloxacin for 2 months and continued with maintenance phase, three times weekly of 450 mg Rifampicin and 450 mg INH until one year. Treatment provided a good result.</em></p> <p><em> </em></p> <p><strong><em>Keywords</em></strong><em>: tuberculosis; lupus vulgaris; therapeutic trial</em></p>}, number={5}, journal={Journal of Medicine and Health}, author={Puspitasari, Dian and Henrica, Feilicia}, year={2020}, month={Feb.} }