Pengaruh Diabetes Melitus Tipe 2 terhadap Sarkopenia pada Lansia

Authors

  • Anindya Rosma Fakultas Kedokteran Universitas Kristen Maranatha
  • Decky Gunawan Bagian Faal Fakultas Kedokteran Universitas Kristen Maranatha
  • Cindra Paskaria Bagian Ilmu Kesehatan Masyarakat Universitas Kristen Maranatha

DOI:

https://doi.org/10.28932/jmh.v4i2.2886

Keywords:

diabetes melitus tipe 2, lansia, sarkopenia

Abstract

Sarkopenia adalah penurunan massa otot dan umum terjadi pada lansia. Sarkopenia dikaitkan dengan proses selular seperti penurunan faktor-faktor anabolisme otot dan peningkatan faktor-faktor inflamasi yang berdampak pada proses katabolisme otot. Terjadinya sarkopenia dikaitkan dengan bermacam-macam faktor risiko, salah satunya adalah diabetes melitus tipe 2 (DM tipe 2). DM adalah penyakit metabolik dengan karakteristik hiperglikemia yang terjadi akibat kelainan sekresi insulin, kerja insulin atau kedua-duanya. Tujuan penelitian ini adalah untuk mengetahui pengaruh DM tipe 2 terhadap sarkopenia pada lansia. Metode penelitian adalah studi observasional analitik dengan desain cross-sectional. Terdapat 60 subjek penelitian yang memenuhi kriteria inklusi dan eksklusi, yang terdiri dari 22 lansia yang menderita DM tipe 2 dan 38 lansia yang tidak menderita DM tipe 2. Analisis data menggunakan uji statistik Chi-Square pada tabel 2x2 dengan α = 0,05. Hasil penelitian menunjukkan bahwa proporsi penderita sarkopenia pada lansia yang menderita DM tipe 2 (61,9 %) lebih banyak daripada lansia yang tidak menderita DM tipe 2 (38,1) dengan nilai p = 0,003. Nilai Odds Ratio sebesar 5,471, menunjukkan bahwa lansia yang memiliki riwayat DM tipe 2 berisiko 5 kali lebih besar mengalami sarkopenia. Dapat disimpulkan terdapat pengaruh DM tipe 2 terhadap sarkopenia pada lansia.

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Published

2022-08-31

How to Cite

1.
Rosma A, Gunawan D, Paskaria C. Pengaruh Diabetes Melitus Tipe 2 terhadap Sarkopenia pada Lansia. J. Med. Health [Internet]. 2022Aug.31 [cited 2024Apr.25];4(2):145-53. Available from: https://journal.maranatha.edu/index.php/jmh/article/view/2886

Issue

Vol. 4 No. 2 (2022)

Section

Articles

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Copyright (c) 2022 Anindya Rosma, Decky Gunawan, Cindra Paskaria

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