Prevalence of Delirium and Its Clinical Outcome in Adult Filipino Patients Admitted in The Intensive Care Unit

  • Abram P Tanuatmadja De Los Santos Medical Center, Department of MedicineMaranatha Christian University - Immanuel Hospital, Department of Medicine https://orcid.org/0000-0001-5171-1548
  • Jacqueline R Vea - University of the Philippines - Philippine General Hospital, Department of Clinical Epidemiology- De Los Santos Medical Center, Department of Medicine- Lourdes Hospital, Department of Neurology- Philippines Neurological Association

Abstract

Delirium is common in the ICU setting and is associated with increased morbidity, manpower requirement, and costs. This study aims to investigate the prevalence of delirium and its outcome in terms of 14-days mortality and length of ICU stay in ICU patients. The study was done at a 150-bed tertiary teaching hospital, located in Quezon City, Metro Manila, February to September 2016. This is a prospective studyinvolving 136 adults. Screening for delirium was done within 24 hours of ICU admission using both CAM-ICU scoring method and DSM-IV-TR criteria for delirium. Delirium prevalence was found to be 5.15%. The average age was higher in the subjects positive for delirium (70.14 + 21.15 years versus 60.43 + 16.10 years, p=0.1286). At the time of ICU admission, 11.54% of sedated patients were positive for delirium compared to 3.64% of non-sedated patients, p=0.1513 ;OR 3.457. Delirium was associated with higher 14 days mortality (OR 16.8, p=0.0212). Subjects positive for delirium had 2.74 longer days average ICU stay compared to the other group, with p=0.026. We concluded delirium was associated with higher 14-days mortality and longer ICU stay. Keywords : delirium, prevalence, Intensive Care Unit

Downloads

Download data is not yet available.

References

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders [Internet]. Arlington. 2013. 991 p. Available from: http://encore.llu.edu/iii/encore/record/C__Rb1280248__SDSM-V__P0,2__Orightresult__X3;jsessionid=ABB7428ECBC4BA66625EDD0E0C5AAFA5?lang=eng&suite=cobalt%5Cnhttp://books.google.com/books?id=EIbMlwEACAAJ&pgis=1

Inouye SK, Van Dyck CH, Alessi C a., Balkin S, Siegal a. P, Horwitz RI. Clarifying confusion: The confusion assessment method: A new method for detection of delirium. Ann Intern Med. 1990;113(12):941–8.

Ely EW, Shintani A, Truman B, Speroff T, Gordon SM, Harrell FE, et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. Jama [Internet]. 2004;291(14):1753–62. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15082703

Bergeron N, Skrobik Y, Dubois M-J. Delirium in critically ill patients. Crit Care [Internet]. 2002;6(3):181–2. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=137438&tool=pmcentrez&rendertype=abstract

Luhr OR, Karlsson M, Thorsteinsson a, Rylander C, Frostell CG. The impact of respiratory variables on mortality in non-ARDS and ARDS patients requiring mechanical ventilation. Intensive Care Med [Internet]. 2000;26(5):508–17. Available from: http://www.ncbi.nlm.nih.gov/pubmed/10923723

Montgomery AB, Stager MA, Carrico CJ, Hudson LD. Causes of mortality in patients with the adult respiratory distress syndrome. Am Rev Respir Dis [Internet]. 1985;132(3):485–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/4037521

Girard TD, Pandharipande PP, Ely EW. Delirium in the intensive care unit. Crit Care [Internet]. 2008;12(Suppl 3):S3. Available from: http://ccforum.com/content/12/S3/S3

Ely EW, Inouye SK, Bernard GR, Gordon S, Francis J, May L, et al. Delirium in Mechanically Ventilated Patients. Crit Care Med. 2001;286(21):2703–10.

Ely EW, Inouye SK, Bernard GR, Gordon S, Francis J, May L, et al. Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). JAMA [Internet]. 2001;286(21):2703–10. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11730446

Ely EW, Margolin R, Francis J, May L, Truman B, Dittus R, et al. Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med. 2001;29:1370–9.

Bergeron N, Dubois M-J, Dumont M, Dial S, Skrobik Y. Intensive Care Delirium Screening Checklist: evaluation of a new screening tool. Intensive Care Med [Internet]. 2001;27(5):859–64. Available from: http://link.springer.com/10.1007/s001340100909

Published
2019-08-27
How to Cite
1.
Tanuatmadja A, Vea J. Prevalence of Delirium and Its Clinical Outcome in Adult Filipino Patients Admitted in The Intensive Care Unit. JMH [Internet]. 27Aug.2019 [cited 13Nov.2019];2(4). Available from: https://journal.maranatha.edu/index.php/jmh/article/view/1106
Section
Articles